Connectivity Map . Connection Map Data Viz Project The Connectivity Map is a collection of genome-wide transcriptional expression data from cultured human cells treated with bioactive small molecules and simple pattern-matching algorithms that together enable the discovery of decisive functional connections between drugs, genes, and diseases Here, we report more than a 1,000-fold scale-up of the CMap as part of the NIH LINCS Consortium, made possible by a new, low-cost, high-throughput reduced representation.
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To date, CMap has generated a library containing over 1.5M gene expression profiles from ~5,000 small-molecule compounds, and ~3,000 genetic reagents, tested in multiple cell types The data is used to find the functional connections between drugs, genes, and diseases through the transitory feature of common gene-expression changes.
Global Network Connection. World Map Point and Line Composition Concept The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease This web interface is designed to allow biologists. The data is used to find the functional connections between drugs, genes, and diseases through the transitory feature of common gene-expression changes.
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Source: elamadwzo.pages.dev web mapping Examples of geovisualizations of global connectivity , The Research Article "The connectivity map: using gene-expression signatures to connect small molecules, genes, and disease" (29 Sept 摘要：Connectivity Map 是药物基因组学研究领域的重要数据库，是 计算生物学 和药物筛选研究人员做研究时不得不重视的数据库。 它不仅提供大量宝贵的药物处理人类细胞系前后的基因表达谱数据，而且也提供了基于 模式匹配算法 的在线工具，用户提交合适的基因列表就能得到该数据库中与之相关.
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Source: dlnetsajhg.pages.dev Global network connection. World map point and line composition concept , To date, CMap has generated a library containing over 1.5M gene expression profiles from ~5,000 small-molecule compounds, and ~3,000 genetic reagents, tested in multiple cell types We demonstrate that this "Connectivity Map" resource can be used to find connections among small molecules sharing a mechanism of action, chemicals and physiological processes, and diseases and drugs
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Source: bambeltmrd.pages.dev Connectivity Map (CMap) analysis in MDAMB468 cells exposed to , The ultimate objective of biomedical research is to connect human diseases with the genes that underlie them and drugs that treat them The Broad Institute's Connectivity Map is a collection of genome-wide, transcriptional expression data from cultured human cells
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connectivity_map1 GÉANT Network . But this remains a daunting task, and even the most inspired researchers still have to resort to laborious screens of genetic or chemical libraries. The Research Article "The connectivity map: using gene-expression signatures to connect small molecules, genes, and disease" (29 Sept